HOMERecent Publications

(論文*・国際学会発表) Publications (2003-)

(2021年)

*Statistical and mathematical models for radiotherapy (in press) (2021)
Masahiro Mizuta, Kenneth L. Sutherland, Keiji Koba-shi, Hiroyuki Minami, Hiroyuki Date and Hiroki Shirato.

*Oxygen enhancement ratios of cancer cells after exposure to intensity modulated X-ray fields: DNA damage and cell survival. Physics in Medicine and Biology (2021) 10.1088_1361-6560
Yusuke Matsuya, Stephen J. McMahon, Karl T. Butterworth, Shingo Naijo, Isshi Nara, Yoshie Yachi, Ryo Saga, Masayori Ishikawa, Tatsuhiko Sato, Hiroyuki Date, Kevin M. Prise.

*4‑Methylumbelliferone administration enhances radiosensitivity of human fbrosarcoma by intercellular communication. Scientifc Reports (2021) 11:8258, 10.1038/s41598-021-87850-3 Ryo Saga, Yusuke Matsuya, ReiTakahashi, Kazuki Hasegawa, Hiroyuki Date and Yoichiro Hosokawa.

*Radiation Safety and Public Health for Radiological Professionals: Meeting Report on The 5th Educational Symposium on Radiation and Health (ESRAH) by Young Scientists in 2018. Radiation Environment and Medicine (2021) Vol.10, No.1 48–54 Hiroko Yamashina, Marin Terashima, Joma Oikawa, Shingo Naijo, Tamao Miyao, Yoshie Yachi, Yusuke Matsuya, Masaru Yamaguchi, Takakiyo Tsujiguchi, Ryo Saga, Hu Jun, Goh Valerie Swee Ting, Toshiya Nakamura, Yoichiro Hosokawa, and Hiroyuki Date.

(2020年)

*A Model for Estimating Dose-Rate Effects on Cell-Killing of Human Melanoma after Boron Neutron Capture Therapy, Cells 9(5):1117. (15 pages) doi: 10.3390/cells9051117. (2020)
Yusuke Matsuya, Hisanori Fukunaga, Motoko Omura, Hiroyuki Date

*A theoretical cell-killing model to evaluate oxygen enhancement ratios at DNA damage and cell survival endpoints in radiation therapy. Physics in Medicine and Biology 65: 095006 (12 pages) (2020)
Matsuya Yusuke, Sato Tatsuhiko, Nakamura Rui, Naijo Shingo, Date Hiroyuki

S. Naijo, Y. Matsuya, H. Date. Surviving fraction model of cells exposed to ionizing radiations considering cancer stem cells and their proliferation. The 4th Faculty of Health Sciences (FHS) International Conference, Hokkaido University, Japan, 2019.7.5 (1min-Oral and Poster)

T. Miyao, Y. Matsuya, H. Date. Radio-sensitivity of the cells exposed to ionizing radiations considering the bystander effect. The 4th Faculty of Health Sciences (FHS) International Conference, Hokkaido University, Japan, 2019.7.5 (1min-Oral and Poster)

Y. Yachi, M. Niwa, Y. Yoshii, Y. Matsuya, H. Date. Evaluation of the Biological Impact by Mammographic Low-Energy X-rays. The 4th Faculty of Health Sciences (FHS) International Conference, Sapporo, Hokkaido, Japan, 2019.7.5 (1min-Oral and Poster)

A. Yamashita, H. Date, A challenge for detecting Japanese pneumonia from chest X-ray images. The 4th Faculty of Health Sciences (FHS) International Conference, Hokkaido University, Japan, 2019.7.5 (1min-Oral and Poster)

Y. Matsuya, Y. Satou, N. Hamada, H. Date, M. Ishikawa, T. Sato. DNA damage following localized exposure to a Cs-bearing microparticle. The 16th International Congress of Radiation Research (ICRR), Manchester, UK, 2019.8.25-29

T. Miyao, Y. Matsuya, H. Date. Model estimation for the uncertainties of treatment planning in fractionated radiotherapy. The 6th meeting of educational symposium of radiation and health (ESRAH), Hirosaki, Aomori, Japan, 2019.9.14 (1min-Oral and Poster)

S. Naijo, Y. Matsuya, H. Date. Measurements of cell surviving fraction for non-uniform irradiation fields. The 6th meeting of educational symposium of radiation and health (ESRAH), Hirosaki, Aomori, Japan, 2019.9.14 (1min-Oral and Poster)

Y. Yachi, Y. Yoshii, Y. Matsuya, H. Date. Electron track structure analysis for update of cross sections. The 6th meeting of educational symposium of radiation and health (ESRAH), Hirosaki, Aomori, Japan, 2019.9.14 (1min-Oral and Poster)

R. Seino, H. Date. A model analysis of cell survival after irradiations considering on repair probabilities of the lesions as time elapses. The 6th meeting of educational symposium of radiation and health (ESRAH), Hirosaki, Aomori, Japan, 2019.9.14 (1min-Oral and Poster)

(2019年)

*Assessment of Ionizing Radiation Effects on the Hematological Parameters of Radiation-Exposed Workers.
Atom Indonesia 45 (2): 123-129 (2019)
H.N.E. Surniyantoro, T. Rahardjo, Y. Lusiyanti, N. Rahajeng, A.H. Sadewa, P. Hastuti and H. Date

*Track Structure Study for Energy Dependency of Electrons and X-rays on DNA Double-Strand Break Induction.
Scientific Reports 9: 17649 (2019), 10.1038/s41598-019-54081-6
Yoshie Yachi, Yuji Yoshii, Yusuke Matsuya, Ryosuke Mori, Joma Oikawa, and Hiroyuki Date

*DNA damage induction during localized chronic exposure to an insoluble radioactive microparticle. Scientific Reports 9 (in press) (2019)
Yusuke Matsuya, Yukihiko Satou, Nobuyuki Hamada, Hiroyuki Date, Masayori Ishikawa, and Tatsuhiko Sato

*Intensity Modulated Radiation Fields Induce Protective Effects and Reduce Importance of Dose-Rate Effects. Scientific Reports 9 (in press) (2019)
Yusuke Matsuya, Stephen McMahon, Mihaela Ghita, Yuji Yoshii, Tatsuhiko Sato, Hiroyuki Date, and Kevin Prise

*Determination of appropriate conversion factors for calculating size-specific dose estimates based on X-ray CT scout images after miscentering correction. Radiological Physics and Technology (in press) (2019)
Marin Terashima, Kazufusa Mizonobe, Hiroyuki Date.

*3D Transformation Matrix Calculation and Pixel Intensity Normalization for the Dual Focus Tracking System. Journal of Medical and Biological Engineering (in press) (2019)
Kenneth Sutherland, Toshiyuki Hamada, Masayori Ishikawa, Naoki Miyamoto, Masahiro Mizuta, Hiroyuki Date, Hiroki Shirato.

*Radio-resistance analysis in high-dose range of prostate cancer cells including cancer stem cells based on a stochastic model. Journal of Radiation Research, 2019, pp.1-10 doi: 10.1093/jrr/rrz011 (2019)
Ryo Saga, Yusuke Matsuya, Rei Takahashi, Kazuki Hasegawa, Hiroyuki Date, Yoichiro Hosokawa.

*Investigation of dose-rate effects and cell-cycle distribution under protracted exposure to ionizing radiation for various dose-rates. Scientific Reports 8: 8287 (2018)
Yusuke Matsuya, Stephen J. McMahon, Kaori Tsutsumi, Kohei Sasaki, Go Okuyama, Yuji Yoshii, Ryosuke Mori, Joma Oikawa, Kevin M. Prise, Hiroyuki Date.

*Polymorphism of XRCC1 Gene Exon 6 (Arg194Trp) in Relation to Micronucleus Frequencies in Hospital Radiation Workers. Atom Indonesia 44 (2): 105-111 (2018), https://doi.org/10.17146/aij.2018.770
H.N.E. Surniyantoro, Y. Lusiyanti, T. Rahardjo, D. Tetriana, S. Nurhayati and H. Date.

*Meeting Report on “The 4th Educational Symposium on Radiation and Health (ESRAH) by Young Scientists in 2017”. Radiation Environment and Medicine 7 (2): 121-124 (2018)
Ryo Saga, Takakiyo Tsujiguchi, Masaru Yamaguchi, Yasuyo Fukushi, Yohei Fujishima, Yusuke Matsuya, Joma Oikawa, Marin Terashima, Hiroyuki Date, Toshiya Nakamura and Yoichiro Hosokawa.

Fundamental Study for Radioresistance Prediction in Prostate Cancer Using Stochastic model. 9th International Conference on High Level Environmental Radiation Areas - For Understanding Chronic Low-Dose-Rate Radiation Exposure Health Effects and Social Impacts(ICHLERA 2018), 2018.9.24-27, Hirosaki, Aomori, Japan
R. Saga, Y. Matsuya, R. Takahashi, K. Hasegawa, H. Date, Y. Hosokawa.

Examination of dose distribution in 320-row multi detector CT (MDCT). The 5th meeting of educational symposium of radiation and health (ESRAH), 2018.9.29-30, Sapporo, Hokkaido, Japan (Poster)
M. Terashima, K. Mizonobe, Y. Matsuya, H. Date.

Cell surviving fraction model for multi-fractionated radiotherapy considering cancer stem cells (CSCs). The 5th meeting of educational symposium of radiation and health (ESRAH), 2018.9.29-30, Sapporo, Hokkaido, Japan (Poster)
S. Naijyo, Y. Matsuya, H. Date.

Estimation of biological effect on normal and tumor cells in IMRT. The 5th meeting of educational symposium of radiation and health (ESRAH), 2018.9.29-30, Sapporo, Hokkaido, Japan (Poster)
T. Miyao, Y. Matsuya, H. Date.

Effects of X-rays energy spectrum and electron track structure on DNA damage. The 5th meeting of educational symposium of radiation and health (ESRAH), 2018.9.29-30, Sapporo, Hokkaido, Japan (Poster)
Y. Yachi, Y. Yoshii, Y. Matsuya, H. Date.

Modeling for colony formation of human lens epithelial cells following ionizing radiation exposure. The 5th meeting of educational symposium of radiation and health (ESRAH), 2018.9.29-30, Sapporo, Hokkaido, Japan (Poster)
J. Oikawa, Y. Matsuya, N. Hamada, H. Date.

Cell responses of lung cancer after exposure to X-rays following in-field and out-of-field configuration. The 18th AOCMP & The 16th SECOMP, 2018.11.11-14, Connexion Convention & Event Centre Bangsar South, Kuala Lumpur, Malaysia (Oral)
C. Yu, Y. Matsuya, M. Ishikawa, H. Date.

Micro- and nano-dosimetric analyses of the energy deposition by ionizing radiations. The 18th AOCMP & The 16th SECOMP, 2018.11.11-14, Connexion Convention & Event Centre Bangsar South, Kuala Lumpur, Malaysia (Oral)
Y. Yachi, Y. Yoshii, Y. Matsuya, H. Date.

教育講座-放射線技術学を用いた先端生命科学研究- 14. 放射線照射後の微視的物理過程を考慮した細胞動態モデル解析. 日本放射線技術学会雑誌第75巻第4号, 1-10 (2019)
伊達 広行.

診療放射線基礎テキストシリーズ2「放射線物理学」:第4章 物質との相互作用 4.2 電子,p92-111.共立出版,2019.3.10
伊達 広行.

(2018年)

*Integrated Modelling of Cell Responses after Irradiation for DNA-Targeted Effects and Non-Targeted Effects. Scientific Reports 8, 4849- (2018)
Yusuke Matsuya, Kohei Sasaki, Yuji Yoshii, Go Okuyama and Hiroyuki Date.

*Estimation of the radiation-induced DNA double-strand breaks number considering cell cycle and absorbed dose per cell nucleus. J. Radiat. Res. 59, 253-260 (2018), https://doi.org/10.1093/jrr/rrx097
R. Mori, Y. Matsuya, Y. Yoshii, H. Date.

*Markov chain Monte Carlo analysis for the selection of a cell-killing model under high-dose-rate irradiation. Med. Phys. 44 (10): 5522-5532 (2017).
Y. Matsuya, T. Kimura, H. Date.

*Comparison of the average surviving fraction model with the integral biologically effective dose model for an optimal irradiation scheme. J. Radiat. Res. Vol. 59, No. S, i32-i39 (2018), doi: 10.1093/jrr/rrx084
Ryo Takagi, Yuriko Komiya, Kenneth L. Sutherland, Hiroki Shirato, Hiroyuki Date and Masahiro Mizuta.

Computational estimation of the number of DNA double-strand breaks per nucleus in mammalian cells after X-ray exposure in consideration of cell cycle. The 3rd faculty of health sciences (FHS), 2017.7.07, Sapporo, Hokkaido, Japan. (Poster)
R. Mori, Y. Matsuya, Y. Yoshii, H. Date.

Estimation of OER in consideration of LET and oxygen partial pressure by the Microdosimetric-Kinetic model. The 3rd faculty of health sciences (FHS), 2017.7.07, Sapporo, Hokkaido, Japan. (Poster)
R. Yamada, Y. Matsuya, H. Date.

Dose estimation by size-specific dose estimate (SSDE) on the pelvic region in cone-beam CT. The 3rd faculty of health sciences (FHS), 2017.7.07, Sapporo, Hokkaido, Japan. (Poster)
M. Terashima, K. Mizonobe, H. Date.

Suggestion of a cell cycle model for long term exposure. The 2nd FHS Intercational Conference, 2017.7.7, Sapporo, Hokkaido, Japan. (Oral and Poster)
Joma Oikawa,Yusuke Matsuya, Tetsuya Sakashita, Ryosuke Mori, Hiroyuki Date.

Verification of size-specific dose estimate (SSDE) calculation method for truncated X-ray CT images. The 43rd Annual Meeting of European Radiation Research Society (ERRS), 2017.9.4-8, Essen, Germany. (Poster)
M. Terashima, K. Mizonobe, H. Date.

A model analysis to estimate the number of DNA double-strand breaks in cells exposed to X-rays. The 43rd Annual Meeting of the European Radiation Research Society, Universitatsklinikum Essen, 2017.9.4-8, Essen, Germany. (Poster)
R. Mori, Y. Matsuya, Y. Yoshii, H. Date.

Modelling of oxygen enhancement ratio in consideration of LET and oxygen partial pressure by using a microdosimetric-kinetic model. The 43rd Annual Meeting of the European Radiation Research Society, Universitatsklinikum Essen, 2017.9.4-8, Essen, Germany. (Poster)
R. Yamada, Y. Matsuya, H. Date.

Application of the IMK model to cell survival curves following the exposure to intensity modulated radiation fields. The 43rd Annual Meeting of the European Radiation Research Society, Universitatsklinikum Essen, 2017.9.4-8, Essen, Germany. (Oral and Poster)
Y. Matsuya, SJ. McMahon, KM. Prise, H. Date.

A simulation study for both of the targeted and untargeted effect on the uniformly irradiated cells, 43rd Annual Meeting of the European Radiation Research Society, Universitatsklinikum Essen, 2017.9.4-8, Essen, Germany. (Symposium)
K. Sasaki, Y. Matsuya, Y. Yoshii, T. Sanada, Y. Yaegashi, and H. Date.

Verification of size-specific dose estimate (SSDE) calculation method for truncated X-ray CT images of thoracicoabdominal and pelvic regions. The 4th meeting of educational symposium of radiation and health (ESRAH), 2017.9.23-24, Hirosaki, Aomori, Japan. (Poster)
M. Terashima, K. Mizonobe, H. Date.

Mathematical estimation of the number of DNA double-strand breaks induced by radiation exposure. The 4th meeting of educational symposium of radiation and health (ESRAH), Hirosaki University, 2017.9.23-24, Hirosaki, Aomori, Japan. (Poster)
R. Mori, Y. Matsuya, Y. Yoshii, H. Date.

Estimation of OER by function considering variation of LET, dose rate and oxygen partial pressure. The 4th meeting of educational symposium of radiation and health (ESRAH), Hirosaki University, Hirosaki, 2017.9.23-24, Hirosaki, Aomori, Japan. (Poster)
R. Yamada, Y. Matsuya, H. Date.

Effects of intercellular signalling on sub-lethal damage repair between fractionation doses following intensity modulated radiation field. The 4th meeting of educational symposium of radiation and health (ESRAH), Hirosaki University, 2017.9.23-24, Hirosaki, Aomori, Japan. (Poster)
Y. Matsuya, Stephen J. McMahon, Mihaela Ghita, Kevin M. Prise.

A cell cycle model for long term exposures of ionizing radiations. The 4th meeting of educational symposium of radiation and health (ESRAH), 2017.9.23-24, Hirosaki, Aomori, Japan. (Oral and Poster)
Joma Oikawa, Tetsuya Sakashita,Yusuke Matsuya, Ryosuke Mori, Hiroyuki Date.

(2017年)

*Educational Activity for the Radiation Emergency System in the Northern Part of Japan: Meeting Report on “The 3rd Educational Symposium on Radiation and Health (ESRAH) by Young Scientists in 2016”. Radiation Research 187, 641-646 (2017)
Y. Matsuya, T. Tsujiguchi, M. Yamaguchi, T. Kimura, R. Mori, R. Yamada, R. Saga, Y. Fujishima, H Date.

*Inorganic polyphosphate enhances radio-sensitivity in a human non-small-cell lung cancer cell line, H1299. Tumor Biology 39(6), 1-6 (2017)
K. Tsutsumi, Y. Matsuya, T. Sugahara, M. Tamura, S. Sawada, S. Fukura, H. Nakano, H. Date.

*Spatial distributions of dose enhancement around a gold nanoparticle at several depths of proton Bragg peak. Nuclear Instruments and Methods in Physics Research Section B 384, 113-120 (2016) doi.org/10.1016/j.nimb.2016.08.013
Jihun Kwon, Kenneth Sutherland, Takayuki Hashimoto, Hiroki Shirato and Hiroyuki Date.

*Modeling of cell survival with change of DNA amount during protracted irradiation. Journal of Radiation Research 58(3): 302-312 (2017) doi: 10.1093/jrr/rrw110
Yusuke Matsuya, Kaori Tsutsumi, Kohei Sasaki, Yuji Yoshii, Takaaki Kimura and Hiroyuki Date.

*Report on the 2nd Educational Symposium on RADIATION AND HEALTH by Young Scientists (ESRAH2015). Radiation Emergency Medicine 2016, 5(1), 15-24.
T. Tsujiguchi, M. Yamaguchi, N. Nanashima, M. Chiba, S. Terashima, Y. Fujishima, Y. Matsuya, J. Kwon, T. Nakamura.

Mathematical analysis of the cell viability under low dose-rate exposure: the change of DNA amount during the protracted irradiation. 42nd Annual Meeting of the European Radiation Research Society, 2016.9.4-8, Royal Tropical Institute, Amsterdam, Netherlands. (Poster)
Y. Matsuya, K. Tsutsumi, K. Sasaki, Y. Yoshii, T. Kimura, H. Date.

Determination of cell surviving fraction for radiotherapy in fractionated irradiation considering dose rates and repopulation of tumor cells. 42nd Annual Meeting of the European Radiation Research Society, 2016.9.4-8, Royal Tropical Institute, Amsterdam, Netherlands. (Poster)
T. Kimura, Y. Matsuya, H. Date.

Estimation of DNA damage kinetics in both targeted and non-targeted cells using a stochastic model with the microdosimetric analysis. The 62nd Radiation Research Society (RRS) Annual Meeting in Waikoloa, Hawaii, 2016.10.16-19. (Poster)
K. Sasaki, Y. Matsuya, H. Date.

A Cell-killing Model of Targeted and Non-Targeted Effects Based on Microdosimetry and Biological Processes. The 3rd meeting of educational symposium of radiation and health (ESRAH), 2016.10.01-02., Sapporo, Hokkaido, Japan. (Oral & Poster)
Y. Matsuya, K. Sasaki, Y. Yoshii, G. Okuyama, T. Kimura, H. Date.

Probability of radiation-induced DNA double-strand breaks in statistical considerations for radiation energy deposition and cell cycle. The 3rd meeting of educational symposium of radiation and health (ESRAH), 2016.10.01-02, Sapporo, Hokkaido, Japan. (Oral & Poster)
R. Mori, Y. Matsuya, Y. Yoshii, H. Date.

Uncertainty assessment of OER for reoxygenated tumor. The 3rd meeting of educational symposium of radiation and health (ESRAH), 2016.10.01-02, Sapporo, Hokkaido, Japan. (Oral & Poster)
R. Yamada, Y. Matsuya, H. Date.

Impacts of electron collision cross sections on electron track simulations in liquid water. The 3rd meeting of educational symposium of radiation and health (ESRAH), 2016.10.01-02, Sapporo, Hokkaido, Japan. (Oral & Poster)
T. Kimura, Y. Matsuya, Y. Yoshii, H. Date.

Biophysical modeling for targeted and non-targeted effects on cells after irradiation. The 22nd International Conference on Medical Physics (ICMP) 2016, Shangri-La Hotel, Bangkok, Thailand, 2016.12.09-12, Bangkok, Thailand. (e-Poster & Oral)
Y. Matsuya, K. Sasaki, Y. Yoshii, H. Date.

Optimization of the irradiation scheme in radiotherapy focusing on the dose and dose rate to the tumor and organs at risk. The 22nd International Conference on Medical Physics (ICMP) 2016, Shangri-La Hotel, Bangkok, Thailand, 2016.12.09-12, (e-Poster & Oral)
R. Yamada, Y. Matsuya, H. Date.

Probability estimation of radiation-induced DNA double-strand breaks in the cell nucleus. The 22nd International Conference on Medical Physics (ICMP) 2016, Shangri-La Hotel, Bangkok, Thailand, 2016.12.09-12, (e-Poster & Oral)
R. Mori, Y. Matsuya, Y. Yoshii, H. Date.

*Size-specific dose estimation (SSDE)算出のためのsize correction factorの検討.日本放射線技術学会雑誌第72巻第9号 727-734 (2016)
溝延 数房,白石 祐太,中野 聡,福田 千晶,浅沼 治,原田 耕平,伊達 広行.

(2016年)

*Optimization of the fractionated irradiation scheme considering physical doses to tumor and organ at risk based on dose-volume histograms. Medical Physics 42 (11), 6203-6210 (2015)
Y. Sugano, M. Mizuta, S. Takao, H. Shirato, K.L. Sutherland, H. Date.

*Study on electron transport in hydrocarbon gases. Journal of Applied Physics, 117, 133302, 1-5 (2015)
H. Hasegawa and H. Date.

*Report on the 2nd Educational Symposium on RADIATION AND HEALTH by Young Scientists (ESRAH2015). Radiation Emergency Medicine, 5(1), 15-24 (2015)
T. Tsujiguchi, M. Yamaguchi, N. Nanashima, M. Chiba, S. Terashima, Y. Fujishima, Y. Matsuya, J. Kwon, T. Nakamura.

Radiosensitizing effects of gold nanoparticles in proton and X-ray irradiations. 2nd meeting of educational symposium of radiation and health (ESRAH), Hirosaki, Japan, (Poster) 5/23-24 (2015)
J Kwon, K L Sutherland, T Hashimoto, H Date.

Dose distribution around gold nanoparticles in proton beam irradiation. 15th International Congress of Radiation Research (ICRR), posters.pp.959, Kyoto, Japan, (Poster) 5/25-29 (2015)
J Kwon, K L Sutherland, T Hashimoto, H Date.

Monte Carlo simulation of the radio sensitizing effect by gold nanoparticles: comparison between proton and X-ray irradiation. World Congress on Medical Physics and Biomedical Engineering 2015, Toronto, Canada, (Oral) 6/7-17 (2015)
J Kwon, K L Sutherland, T Hashimoto, H Date.

Application of gold nanoparticles as a radio sensitizer: comparison between protons and X-rays. 2nd FHS International Conference, Sapporo, Japan, (Oral+Poster) 7/3 (2015)
J Kwon, K L Sutherland, T Hashimoto, H Date.

The evaluation of size correction factor the SSDE in 320 rows ADCT scanning,The 2nd Educational Symposium on RADIATION AND HEALTH for Young Scientists, Hirosaki university, (Poster) 5/ 23 (2015)
K Mizonobe, C Fukuda, Y Shiraishi, S Nakano, O Asanuma, H Takeda, H Date.

Influence of dose delivery rate on the fractionated radiotherapy. 2nd FHS International Conference, Hokkaido University, Sapporo, Japan, (Oral+Poster) p7, 7/3 (2015)
T Kimura, Y Matsuya, H Date.

Dose rate effect on cell survival in the fractionated radiotherapy. 2nd meeting of educational symposium of radiation and health (ESRAH), Hirosaki University, Aomori, Japan, 5/23-24 (2015) (Poster)
T. Kimura, Y. Matsuya, H. Date.

Cell-killing model considering DNA damage repair and cell phase. 2nd meeting of educational symposium of radiation and health (ESRAH), Hirosaki University, Aomori, Japan, 5/23-24 (2015) (Poster)
Y. Matsuya, K. Sasaki, Y. Yoshii, H. Date.

Influence of two types of DNA repair pathways on the surviving fraction of cells exposed to radiations. 15th International Congress of Radiation Research, Kyoto International Conference center, Kyoto, Japan, 5/25-29 (2015) (Poster)
Y. Matsuya, K. Sasaki, Y. Yoshii, H. Date.

Effects of secondary electrons on DNA double-strand breaks after photon irradiation. 2nd meeting of educational symposium of radiation and health (ESRAH), Hirosaki University, Aomori, Japan, 5/23-24 (2015) (Poster)
Y. Yoshii, Y. Matsuya, K. Sasaki, H. Date.

教育講座-モンテカルロシミュレーションの放射線技術への利用-12.モンテカルロ法の将来展望.日本放射線技術学会雑誌第71巻第8号 pp.699-707 (2015)
伊達広行.


(2015年)

*Cluster analysis for the probability of DSB site induced by electron tracks. Nuclear Instruments and Methods in Physics Research Section B, 350, 55?59 (2015) doi: 10.1016/j.nimb.2015.03.025
Y. Yoshii, K. Sasaki, Y. Matsuya, H. Date.

*Dose distribution of electrons from gold nanoparticles by proton beam irradiation. International Journal of Medical Physics, Clinical Engineering and Radiation Oncology, 2015, 4, 49-53 (2015)
Jihun Kwon, Kenneth Sutherland, Takayuki Hashimoto, Hiroyuki Date.

*Evaluation of the cell survival curve under radiation exposure based on the kinetics of lesions in relation to dose-delivery time. Journal of Radiation Research, 56.1, 90?99 (2015) doi: 10.1093/jrr/rru090
Y Matsuya, K Tsutsumi, K Sasaki, H Date.

Computational analysis of the impact of radicals on the non-targeted effects. 2nd International Conference on Radiological Sciences and Technology, Sapporo Convention Center, Sapporo, (Oral) (p.68), 10/10 (2014)
K Sasaki, Y Yoshii, Y Matsuya, H Date.

Monte Carlo Simulation for the Impact of Reactive Oxygen Species on the Radiation-Induced Bystander Effects. 7th Korea-Japan Joint Meeting on Medical Physics, BEXCO, Busan, Korea, (Oral), 9/25-27 (2014)
K Sasaki, Y Yoshii, Y Matsuya, H Date.

A Computational Approach to the DNA Damage Induced by Electron Tracks using The DBSCAN Algorithm. 1st meeting of educational symposium of radiation and health (ESRAH), Hirosaki, Aomori, Japan. (Oral and Poster) p.36, 9/21-22 (2014)
Y Yoshii, Y Matsuya, K Sasaki, H Date.

Estimation of DNA Damage under Low-LET Irradiation according to Distribution of Distance between Interaction’s Events using Monte Carlo Simulation. 41th Annual Meeting of the European Radiation Research Society, Paradise Mare Conference Centre, Aldemar Hotel, Rhodes Greece, (Poster) p215, 9/14-19 (2014)
Y Yoshii, K Sasaki, Y Matsuya, H Date.

Monte Carlo simulation of the electron production by proton beam irradiation to gold particles. 7th Korea-Japan Joint Meeting on Medical Physics, BEXCO, Busan, Korea, 9/25-27 (2014)
J Kwon, K L Sutherland, T Hashimoto, H Date.

Monte Carlo simulations of proton beam irradiation of gold particles. 1st meeting of educational symposium of radiation and health (ESRAH), Hirosaki, Aomori, Japan, (Oral and Poster) p.25, 9/21-22 (2014)
J Kwon, K L Sutherland, T Hashimoto, H Date.

A Novel Technique for Optimizing the Dose Fractionation Regimen Based on the Universal Survival Curve with Tumor Repopulation 2014. Radiological Society of North America (RSNA2014): 100th Scientific Assembly and Annual Meeting, Chicago, USA, 11/30-12/5 (2014)
Y Sugano, M Mizuta, S Takao, H Shirato, K L. Sutherland, H Date.

A graphical method for selecting the optimal number of fractions and dose per fraction for fractionated radiotherapy, 1st Educational Symposium on Radiation and Health by Young Scientists (ESRAH2014), Hirosaki, Japan, (Oral and Poster) p.24, 9/21-22 (2014)
Y Sugano, M Mizuta, S Takao, H Shirato, K L. Sutherland, H Date.

Quantitative Estimation of DNA Lesions in the Cell nucleus in Consideration of the Dose Rate. 2nd International Conference on Radiological Sciences and Technology, Sapporo Convention Center, Sapporo, (Oral) p.64, 10/10 (2014)
Y Matsuya, Y Yoshii, K Tsutsumi, K Sasaki, H Date.

Dose Rate Effects of Standard X-rays exposure on Biological Cells. 1st meeting of educational symposium of radiation and health (ESRAH), Hirosaki, Aomori, Japan, (Oral and Poster) p.36, 9/21-22 (2014)
Y Matsuya, Y Yoshii, K Sasaki, H Date.

Dose Rate Effects on the Cell Survival Curve at High Dose. 41th Annual Meeting of the European Radiation Research Society, Paradise Mare Conference Centre, Aldemar Hotel, Rhodes Greece, (Poster) p.199, 9/14-19 (2014)
Y Matsuya, K Tsutsumi, K Sasaki, Y Yoshii, H Date.

教育講座-モンテカルロシミュレーションの放射線技術への利用-3.モンテカルロシミュレーションの放射線医療への応用.日本放射線技術学会雑誌第70巻第8号pp.827-838 (2014)
ケネス・サザランド、白石 祐太、伊達 広行.

教育講座-モンテカルロシミュレーションの放射線技術への利用-2.モンテカルロ法とシミュレーション.日本放射線技術学会雑誌第70巻第7号pp.705-714 (2014)
伊達 広行、吉井 勇治、佐々木 恒平.

教育講座-モンテカルロシミュレーションの放射線技術への利用-1.モンテカルロ法の原理.日本放射線技術学会雑誌第70巻第6号pp.582-587 (2014)
伊達 広行.

シミュレーションによる放射線誘発バイスタンダー効果の動態解析.北海道放射線技術雑誌 77、pp.34-35 (2014)
高瀬 崚研、佐々木 恒平、伊達 広行.

モンテカルロ法を用いた光子線の生物学的線量の推定.北海道放射線技術雑誌 77、pp.30-31 (2014)
吉井 勇治、佐々木 恒平、三浦 貴智、伊達 広行.


(2014年)

*Quantitative estimation of DNA damage by photon irradiation based on the microdosimetric-kinetic model. Journal of Radiation Research, 55: 484-493 (2014) doi:10.1093/jrr/rrt222
Yusuke Matsuya, Yosuke Ohtsubo, Kaori Tsutsumi, Kohei Sasaki, Rie Yamazaki, and Hiroyuki Date.

*A formulation of cell surviving fraction after radiation exposure. Radiological Physics and Technology (2014) 7: 148-157 (2014) doi: 10.1007/s12194-013-0244-z
Hiroyuki Date, Kosuke Wakui, Kohei Sasaki, Takahiro Kato, and Takeshi Nishioka.

*Influence of respiration on dose calculation in stereotactic body radiotherapy of the lung. Radiological Physics and Technology (2014) 7:284-289 (2014) doi:10.1007/s12194-014-0263-4
Rie Yamazaki, Rikiya Onimaru, Norio Katoh, Tetsuya Inoue, Takeshi Nishioka, Hiroki Shirato, Hiroyuki Date.

In silico modeling for the radiation-induced bystander effect with confluent cell monolayers. 40th Annual Meeting of the European Radiation Research Society, W-58, Dublin (Ireland), 2013.9.1-5
Kohei Sasaki, Hiroyuki Date, Kaori Tsutsumi, Yusuke Matsuya, and Akio Itoh.

Estimation of DNA damage related to RBE with photon irradiation. 40th Annual Meeting of the European Radiation Research Society, M-14, Dublin (Ireland), 2013.9.1-5
Yusuke Matsuya, Yosuke Ohtsubo, Kaori Tsutsumi, Kohei Sasaki, Rie Yamazaki, and Hiroyuki Date.

A Mathematical Framework to Select Fractionation Regimen based on Physical Dose Distribution for Proton Therapy The 52nd Annual Conference of the Particle Therapy Co-Operative Group (PTCOG 52), Congress Center in Essen, Germany, 2?8 June 2013
Seishin Takao, Masahiro Mizuta, Hiroyuki Date, Yuriko Komiya, Kenneth L. Sutherland, Rikiya Onimaru, Shinichi Shimizu, and Hiroki Shirato.


(2013年)

Upcoming Dynamic Real-time Tumor-tracking for Lung Cancer: A Preliminary Study of its Validity. Third International Conference on Real-time Tumor-tracking Radiation Therapy with 4D Molecular Imaging Technique, PA-05, p44, Sapporo Convention Center, Sapporo, Japan, 2/8 (2013)
Rie Yamazaki, Seiko Nishioka, Hiroyuki Date, Takao Koike, Hiroki Shirato, Takeshi Nishioka

A Mathematical Method for Estimating Optimal Fractionation Regimen in Radiotherapy, Third International Conference on Real-time Tumor-tracking Radiation Therapy with 4D Molecular Imaging Technique, PA-06, p44, Sapporo Convention Center, Sapporo, Japan, 2/8 (2013)
Seishin Takao, Masahiro Mizuta, Hiroyuki Date, Yuriko Komiya, Kenneth L. Sutherland, Rikiya Onimaru, Hiroki Shirato

「Ⅱ放射性同位元素検査技術学 第1章 放射線同位元素の物理と計測装置」 MT標準臨床検査学 臨床医学総論 p208~p219.小山高敏・戸塚実 編集.医学書院
伊達広行


(2012年)

*A simulation study of the radiation induced bystander effect: Modeling with stochastically-defined signal re-emission. Computational and Mathematical Methods in Medicine, Volume 2012, Article ID 389095, 5pages (2012) doi:10.1155/2012/389095
Kohei Sasaki, Kosuke Wakui, Kaori Tsutsumi, Akio Itoh and Hiroyuki Date

*Graphical representation of the effects on tumor and OAR for determining the appropriate fractionation regimen in radiation therapy planning. Medical Physics 39 (11), 6791-6795 (2012) doi:10.1118/1.4757580
Masahiro Mizuta, Hiroyuki Date, Seishin Takao, Naoki Kishimoto, Kenneth L. Sutherland, Rikiya Onimaru, and Hiroki Shirato

*A mathematical study to select fractionation regimen based on physical dose distribution and the linear-quadratic model. International Journal of Radiation Oncology, Biology, Physics 84, No.3, 829-833 (2012) doi:10.1016/j.ijrobp.2012.01.004
Masahiro Mizuta, Seishin Takao, Hiroyuki Date, Naoki Kishimoto, Kenneth L. Sutherland, Rikiya Onimaru, and Hiroki Shirato

*Investigation of the change in marker geometry during respiration motion: a preliminary study for dynamic-multi-leaf real-time tumor tracking. Radiation Oncology 7:218 (2012) 5pages doi:10.1186/1748-717X-7-218
Rie Yamazaki, Seiko Nishioka, Hiroyuki Date, Hiroki Shirato, Takao Koike, and Takeshi Nishioka

Modeling of Radiation-Induced Bystander Effect with Re-emitting Signals Following the Poisson Statistics. World Congress on Medical Physics and Biomedical Engineering, TH.04/01.1-5, p129, Beijing International Convention Center, Beijing, China, 5/26-31 (2012)
K. Sasaki, H. Date, T. Tsujiguchi, K. Wakui and A. Itoh

Analysis of Cell Surviving Fraction with Non-Lethal Probability for Radiation Exposure. World Congress on Medical Physics and Biomedical Engineering, TH.04/01.2 -1, p129, Beijing International Convention Center, Beijing, China, 5/26-31 (2012)
Kosuke Wakui, Kohei Sasaki, Hiroyuki Date


(2011年)

*Electron Track Analysis for Damage Formation in Bio-Cells. Nucl. Instr. and Meth. B. 269, 1887-1891 (2011)
Y. Yoshii, K.L. Sutherland., H. Date

*Radiation-induced Cancer Cell Repopulation: A possible mechanism implied by experiments using trasplantable mouse-derived sarcoma cell line. Cell Structure and Function 36, 13-20 (2011)
T. Nishioka, M. Yasuda, T. Takeshima, H. Haga, Y. Miyai, K. Shibata, H. Shirato, M, Teduka and H. Date

*Electron Transport Properties in TRIES (HSi(OC2H5)3) Vapor. Jpn. J. Appl. Phys. 50 (2011) 120210-(1-3)
Kosaku Yoshida, Ran Sato, Takuya Yokota, Yasutaka Kishimoto, and Hiroyuki Date

Theoretical Comparison between Availabilities of Single- and Fractionated- Irradiation Therapies. ASTRO's (American Society for Radiation Oncology) 53rd Annual Meeting in Miami Beach, FL on October 2-6, 2011. International Journal of Radiation Oncology*Biology*Physics, Vol.81, Number 2, Supplement, P.728 (2011)
M. Mizuta, S. Takao, H. Date, N. Kishimoto, H. Shirato

A Simulation Study of Radiation Therapy Based on LQ Model. Joint Meeting of the Korea-Japan Conference of Computational Statistics and the 25th Symposium of Japanese Society of Computational Statistics, November 11-12 (2011), HAEUNDAE GRAND HOTEL, Busan, Korea. Proceedings of Joint Meeting of the Korea-Japan Conference of Computational Statistics and the 25th Symposium of Japanese Society of Computational Statistics, 103-106.
Naoki Kishimoto, Yuriko Komiya, Hiroyuki Date, Hiroki Shirato, Masahiro Mizuta

Microdosimetric Kinetic Analysis of the Relation between Energy Distribution of Photon Beam and Lesions Induced in Bio-Cells. The 6th Japan-Korea Joint Meeting on Medical Physics and the 11th Asia-Oceania Congress of Medical Physics. D2-1 (3p), Fukuoka, September (2011)
Y. Ohtsubo, K. Tsutsumi, K. Sasaki, K. Wakui, and H. Date

Modeling of Clustering Properties of the Electron Processes in Bio-Tissues Exposed to Ionizing Radiation. The 6th Japan-Korea Joint Meeting on Medical Physics and the 11th Asia-Oceania Congress of Medical Physics. D2-2 (4p), Fukuoka, September (2011)
Yuji Yoshii, Kohei Sasaki, K.L. Sutherland, and Hiroyuki Date

Trial Study of a New Model for Cell Surviving Fraction. The 6th Japan-Korea Joint Meeting on Medical Physics and the 11th Asia-Oceania Congress of Medical Physics. P-19 (3p), Fukuoka, September (2011)
Kosuke Wakui, Takahiro Kato, Kohei Sasaki and Hiroyuki Date

Microdosimetric Kinetic Analysis of the Lesions in Bio-Cells by Radiation Exposure. 14th International Congress of Radiation Research (ICRR), 40-09, p329, Warsaw, Poland, August (2011)
Y. Ohtsubo, K. Tsutsumi, K. Sasaki, K. Wakui, and H. Date

Computational Approach for Determining the Properties of Low-Energy Electron Track. 14th International Congress of Radiation Research (ICRR), 41-07, p332, Warsaw, Poland, August (2011)
Y. Yoshii, K. Sasaki, K.L. Sutherland, and H. Date


(2010年)

*Nuclear collision processes around the Bragg peak in proton therapy. Radiol. Phys. Technol. 3, 84-92 (2010)
Y. Matsuzaki, H. Date, K.L. Sutherland, Y. Kiyanagi

*A parameter study of pencil beam proton dose distributions for the treatment of ocular melanoma utilizing spot scanning. Radiol. Phys. Technol. 3, 16-22 (2010)
Kenneth Sutherland, Satoshi Miyajima, Hiroyuki Date, Hiroki Shirato, Masayori Ishikawa, Masao Murakami, Mitsuru Yamagiwa, Paul Bolton, Toshiki Tajima

An Interpretation of the Survival Curve for Cells Exposed to X-rays. 9th International Conference on the Effects of Low and Very Low Doses of Ionizing Radiation on Human Health and Biotopes. Barcelona, Spain, 12/13-15 (2010)
H. Date, T. Kato, K. Wakui

Properties of Electron Collisions with Constituent Molecules in Living Cells. Proceedings of International Workshop on Plasmas with Liquids (IWPL2010), P-11, 91-92, Matsuyama, Japan, 3/22-24 (2010)
H. Date, H. Hasegawa, M. Shimozuma


(2009年)

*Properties of electron swarms in CF3I. Applied Physics Letters 95, 101504 (1-3) (2009)
H. Hasegawa, H. Date, M. Shimozuma, and H. Itoh

*Time-of-flight observation of electron swarm in methane. Journal of Applied Physics. 105, 113308 (1-6) (2009)
H. Hasegawa, H. Date, K. Yoshida and M. Shimozuma

*Nanometer site analysis of electron tracks and dose localization in bio-cells exposed to X-ray irradiation. Nucl. Instr. and Meth. B. 267, 1135-1138 (2009)
H. Date, Y. Yoshii, K.L. Sutherland

Statistical properties of radiation damage to bio-cells by X-rays exposure. 8th International Meeting on the Effects of Low Doses and Very Low Doses of Ionizing Radiation on Human Health and Biotopes. LWR21, 115, Windsor Hotel, Barra da Tijuca, Rio de Janeiro, Brazil, 9/28-30 (2009)
H. Date and Y. Yoshii.


(2008年)

Nuclear collision processes around the Bragg peak in proton therapy. The 5th KOREA-JAPAN Joint Meeting on Medical Physics. SS3-R1-1 (3 pages) Jeju Hanwha Resort, Korea, 9/10-12 (2008)
Matsuzaki Y, Date H, Sutherland K L, Kiyanagi Y.


(2007年)

*Electron swarm parameters in water vapour. J. Phys. D: Appl. Phys. 40, 2495-2498 (2007)
Hasegawa H, Date H and Shimozuma M.

*A simple parallelization of GEANT4 on a PC cluster with static scheduling for dose calculations. Journal of Physics: Conference Series 74, 012020 (2007)
Sutherland K L, Miyajima S and Date H.

*Ionization and excitation processes of electrons in liquid water. Nucl. Instr. and Meth. B 265, 515-520 (2007)
Date H, Sutherland K L, Hasegawa H, Shimozuma M.

*Electrical Conductivity of TiO2 Thin Film on Insulator Induced by Radiation Exposure. Japanese Journal of Applied Physics Vol.46, No.1, 417-419 (2007)
Date H, Tomozawa H, Takamasa T, Okamoto K, Shimozuma M.

*TiCl4+CH4+H2材料ガスを用いたイオンエンハンストライオードプラズマCVD法によるTi基板上へのTiC薄膜の堆積 放電学会「放電研究」50巻2号(2007)42-46 (2007)
吉野正樹、下妻光夫、伊達広行

*次世代統合シミュレーション技術3「放射線治療の高度化のための超並列シミュレーションシステム」 情報処理10 Vol.48 No.10 通巻512号 1081-1088 (2007)
斎藤公明、齋藤秀俊、国枝悦夫、成田雄一郎、明上山温、藤崎達也、川瀬貴嗣、金子勝太郎、尾嵜真浩、ホサイン・デロア、平井正明、奥洋平、田島俊樹、山極満、古賀ジェームズ、ティムル・エシロケポフ、セルゲイ・ブラノフ、宮島悟史、岡崎良子、伊達広行、ケン・サザーランド、菱川良夫、村上昌雄

*医療用放射線の物理過程シミュレーション-量子エネルギーのゆくえを探る- 日本放射線技術学会雑誌第63巻第10号 1163-1171 (2007)
伊達広行


(2006年)

*A Novel Real-Time Dosimetry Technique Based on Radiation Induced Sueface Activation. Radiation Protection Dosimetry 120 No.1-4: 373-377 (2006)
Tomozawa H, Takamasa T, Okamoto K, Tujimura N, Date H and Nakata J.

*Inelastic collision processes of low energy protons in liquid water. Radiation Physics and Chemistry 75, 179-187 (2006)
Date H, Sutherland K L, Hayashi T, Matsuzaki Y, Kiyanagi Y.

Monte Carlo Dose Distribution Simulations of Laser-Accelerated Proton Beams. Roadmap for Laser-Accelerated Proton Beams in Medicine. p2-4.Kyoto.03/15-16, 2006
Sutherland K L, Miyajima S, Date H, Yamagiwa M, Tajima T.

Microdosimetric Study of Radiation in Bio-tissue: Electron Collision Processes in Water. World Congress on Medical Physics and Biomedical Engineering, T12 S8 3641, 8/27-9/1, 2006 Seoul, Korea
H. Date, K.L. Sutherland, H. Hasegawa, M. Shimozuma.


(2005年)

*Deposition of SiC films by ion-enhanced plasma vapor deposition using tetramethylsilane + H2. Thin Solid Films 492, 207-211 (2005)
Yoshino M, Shimozuma M, Date H, Itoh H, Tagashira H.

Development of Innovative Radiation Detector Using Radiation Induced Surface Activation. 13th International Conference on Nuclear Engineering, Technical 6-11 Radiation Protection and Safety, ICONE13-50454 (6 pages in all) (Beijing, China) 5/16-20, 2005
Takano M, Hazuku T, Takamasa T, Okamoto K, Date H, Tomozawa H, Tsujimura N.

Execution Speed of Dose Distribution Simulations with GEANT4. The 4th Japan-Korea Joint Meeting on Medical Physics and the 5th Asia-Oceania Congress of Medical Physics. JJMP Vol.25 Supplement No.3-1, 337-339 (2005)
Sutherland K L, Miyajima S, Date H, Yamagiwa M, Tajima T.

Electron Collision Processes in the Bragg Peak Region of Proton in Water. The 4th Japan-Korea Joint Meeting on Medical Physics and the 5th Asia-Oceania Congress of Medical Physics. JJMP Vol.25 Supplement No.3-1, 340-343 (2005)
Date H, Sutherland K L, Hayashi T, Matsuzaki Y, and Kiyanagi Y.


(2004年)

*Radiation Detector Using Radiation Induced Surface Activation. Journal of Nuclear Science and Technology, Sup.4: 152-155 (2004)
Takamasa T, Hazuku T, Tujimura N, Okamoto K, Tomozawa H, Nakata J and Date H.

*小特集「プラズマ応用技術におけるシミュレーション研究」2.低温プラズマ放電の基礎. Journal of Plasma and Fusion Research, 80(2):113-118 (2004)
伊達広行

Monte Carlo Simulation for Designing Radiation Detectors Using Radiation Induced Surface Activation. 11th International Congress of the International Radiaton Protection Association (IRPA11), Madrid, 2004;3g3 (ID:339), ISBN: 84-87078-05-2 (4 pages)
Date H, Tomozawa H, Takamasa T, Okamoto K and Shimozuma M.

Fundamental Study on Designing Radiation Detectors Using Radiation Induced Surface Activation. 11th International Congress of the International Radiaton Protection Association (IRPA11), Madrid, 2004;3h71 (ID:1400) (8 pages)
Takamasa T, Hazuku T, Takano M, Okamoto K, Date H, Tomozawa H, Nakata J and Tsujimura N.


(2003年)

*Electron collision processes in gaseous xenon. Nucl. Instr. & Meth. in Phys. Res. B 207, 373-380 (2003)
H. Date, Y. Ishimaru, M. Shimozuma.

*Development of RISA (Radiation Induced Surface Activation) Detectors for Onsite Sensing and Microdosimetry. Selected Materials of the International Workshop on Radiation Risk ans its Origin at Molecular and Cellular Level, JAERI-Conf 2003-011, 5. 3, 65-75 (2003)
H. Date, H. Tomozawa, T. Takamasa, K. Okamoto and M. Shimozuma.

Radiation detector using radiation induced surface activation. The second iTRS International Symposium on Radiation Safety and Detection Technology (ISORD-2), A6-4, 53 (2003)
T. Takamasa, T. Hazuku, K. Okamoto, N. Tujimura, H. Tomozawa, J. Nakata and H. Date.

Development of Radiation Detector Using Radiation Induced Surface Activation. Radiation Detectors and Their Uses, KEK Proceedings (11 pages) (2003)
T. Takamasa, T. Hazuku, K. Okamoto, N. Tujimura, H. Tomozawa, J. Nakata and H. Date.

Deposition of TiO2 Films by Triode Plasma CVD Method Using TiCl4+O2. The 20th Symposium on Plasma Processing. P2-27, 279-280 (2003)
M. Shimozuma, M. Yoshino, H. Date, K. Satoh, H. Itoh.

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